Background. The use of Ozone because of it’ s antimicrobial effects, healing properties, and also it’ s biocompatibility is suggested nowadays. The aim of this presentation is to review of Ozone therapy in periodontics. Methods. In this presentation, the primary aim is to introduce the chemical features, apparatus, history and the effect of Ozone in periodontal treatment, and secondary objective is to provide a review of articles using Ozone in periodontics. Results. There are several studies using Ozonated water as an irrigator, in periodontal pockets and as an antiseptic agent which show it’ s beneficial effects. Conclusions. According to studies Ozone therapy can be suggested as an adjunctive treatment in periodontology.

In the present study the effect of ozone therapy on hydrofluoric acid (HFA) related eye burn was investigated in rats. A Total 20 healthy male Wistar albino rats (weighing 250 - 300 g with the age of 16 weeks) were used. They were divided into groups (experimental and control groups) of 10 rats being housed individually and fed ad libitum. The HFA (2.00%) burn was created in all animals. The ozonized (20.00 µg O3 mL-1) bi-distilled water was applied as a drop (10.00 µL each drop) every 8 hr for 7 days in the experimental group. At the same time, 0.90% NaCl was applied as drop (10.00 µL each drop) every 8 hr for 7 days in the control group. In the experimental group, intensive inflammation, angiogenesis, epithelial damage and stromal edema were detected in one animal. Epithelial vascularization and stromal edema were seen in four animals. In control group, only two animals’ corneal structures were normal. Inflammation, angiogenesis, epithelial damage, fibrosis, epithelial vascularization and stromal edema were detected in the rest. As a result of this study, it was observed that local usage of ozone therapy had a positive effect on the healing of corneal burns caused by HFA. It was concluded that more ozone-related studies should be done to enlighten the subject.